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利拉鲁肽联合胰岛素治疗2型糖尿病过程中血糖变化及安全性分析 被引量:7

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摘要 目的分析2型糖尿病患者采取利拉鲁肽+胰岛素联合治疗的血糖变化情况及安全性。方法选取2016年1月—2017年6月期间我院收治的78例2型糖尿病患者,随机分为2组,每组39例。2组患者均使用胰岛素进行治疗,研究组在此基础上加用利拉鲁肽,比较2组血糖变化情况及安全性。结果研究组患者空腹血糖、餐后2 h血糖、糖化血红蛋白均低于对照组,但组间比较差异无统计学意义(P>0.05);研究组血糖波动幅度、餐后血糖波动幅度及日间血糖绝对差均低于对照组,胰岛素使用剂量少于对照组,血糖达标时间短于对照组,且不良反应发生率低于对照组,差异均有统计学意义(P<0.05)。结论 2型糖尿病患者采取利拉鲁肽+胰岛素联合治疗效果显著,能改善血糖指数,减少血糖波动情况,降低不良反应发生率,缩短血糖达标时间,减少胰岛素用量,值得临床推广应用。
作者 周瑞君
出处 《基层医学论坛》 2019年第14期1944-1945,共2页 The Medical Forum
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