不同子宫位置子宫肌瘤的高强度聚焦超声消融效果分析

The influence of uterus position on HIFU ablation effect of uterine fibroids

目的比较不同子宫位置子宫肌瘤的高强度聚焦超声(HIFU)消融效果。方法回顾性分析我院HIFU治疗的症状性子宫肌瘤患者372例,所有肌瘤患者根据子宫位置(前位、中位、后位)分组,采用单因素方差分析比较各组患者的基线数据、HIFU消融结果。结果所有患者均顺利完成HIFU治疗。单因素方差分析结果表明,不同子宫位置子宫肌瘤的基线数据差异无统计学意义(P>0.05);前位子宫1 cm3辐照时间显著小于后位子宫(P=0.007),能效因子(EEF)小于后位子宫(P=0.017),差异均有统计学意义。结论前位子宫的子宫肌瘤更容易进行HIFU消融。

Objective To compare high-intensity focused ultrasound(HIFU)ablation effect on uterine fibroids between patients with different uterus positions.Methods The clinical data of 372 patients with symptomatic uterine fibroids,who were treated with HIFU at authors’hospital,were retrospectively analyzed.According to the position of the uterus,the patients were divided into anteverted group,mid-position group and retroverted group.Single factor analysis of variance was used to compare the baseline data of fibroids and HIFU ablation results between each other among the three groups.Results Successful HIFU treatment was accomplished in all patients.The average age of the patients was(39±6)years.Single factor analysis of variance indicated that no statistically significant difference in baseline data of fibroids existed between each other among the three groups(P>0.05).The one cm3 sonication time and energy efficiency factor(EEF)in the anteverted group were significantly smaller than those in the retroverted group,the differences were statistically significant(P=0.007 and P=0.017 respectively).Conclusion Uterine fibroids within an anteverted uterus are more likely to be ablated by HIFU.