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醋酸吲哚实验在卡他莫拉菌快速鉴定中的临床应用 被引量:1

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摘要 目的通过对醋酸吲哚酚(ACIND)实验与经典生化鉴定结果的一致性分析,评价ACIND的临床应用价值。方法选取某院分离的273株卡他莫拉菌(MC)疑似菌株为实验菌株,同时应用ACIND与VITEK-2compact进行鉴定,对鉴定结果进行统计学分析,结合药物敏感性数据,评价其快速检测结果对临床用药的参考价值。结果 273株疑似菌株经生化鉴定为257株MC及16株非MC,257株MC经ACIND鉴定有254株显阳性,而16株非MC中也有6株显阳性或弱阳性。ACIND对MC的灵敏度与特异度分别为98.83%(254/257)与62.50%(10/16),阳性预测值与阴性预测值分别为96.15%(254/260)及76.92%(10/13),Kappa值为0.672。该菌β-内酰胺酶阳性率为99.22%(255/257),对复方磺胺甲噁唑、头孢克诺及头孢呋辛的不敏感率均在20%~30%,对其他抗菌药物不敏感率低于5%。结论 ACIND鉴定结果与经典生化鉴定结果具有较好一致性,结合该地区MC耐药监测数据对临床用药具有较好的指导作用及临床应用前景。
作者 刘岚 王小龙
出处 《检验医学与临床》 CAS 2019年第8期1121-1123,共3页 Laboratory Medicine and Clinic
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