2013—2017年上海市徐汇区糖尿病并发肺结核患者特征登记转归分析

Analysis on registration and outcome of diabetes mellitus complicated with pulmonary tuberculosis patients in Xuhui District of Shanghai from 2013 to 2017

目的分析2013—2017年上海市徐汇区糖尿病并发肺结核患者登记转归情况。方法收集2013—2017年上海市徐汇区结核病管理信息系统、疾病控制信息管理平台、结核病定点医院电子病历等资料;同期糖尿病管理人口数资料来源于疾病控制信息管理平台下的子系统糖尿病信息管理数据。2013-2017年上海市徐汇区共登记活动性肺结核患者1383例,其中.男903例,女480例;糖尿病并发肺结核患者147例(观察组).未并发糖尿病的肺结核患者1236例(对照组)。人口资料来源于上海市徐汇区统计年鉴。对比分析上述两组患者的临床信息。结果2013-2017年上海市徐汇区登记糖尿病并发肺结核患者147例.占全部肺结核登记患者的10.63%(147/1383)。糖尿病患者中并发肺结核登记发病率(54.20/10万,117.18/10万)约为一般人群肺结核登记率(22.86/10万,28.62/10万)的2.18-4.72倍。观察组患者平均年龄为(64.26+1.06)岁、男性患者占81.0%(119/147)、涂阳患者占57.1%(84/147)、就诊延误时间中位数(四分位数)[M(Q,Q)]为14.0(5.0.32.0)d、治疗疗程为(10.90+2.68)个月;对照组患者平均年龄为(43.75±0.59)岁、男性患者占63.4%(784/1236)、涂阳患者占37.1%(458/1236)、就诊延误时间[M(Q1,3)]为11.5(2.0,27.0)d、治疗疗程为(10.09±3.14)个月,差异均有统计学意义(t=11.73、X^2=17.80、X^2=22.25、Z=—2.22,t=3.16,P值均<0.05)。结论糖尿病并发肺结核患者登记发病率高于一般人群.平均年龄、男性比例、涂阳比例、就诊延迟时间、治疗疗程均高于未并发糖尿病的肺结核患者。

Objective To analyze the registration and outcome of diabetes mellitus complicated with pulmonary tuberculosis patients in Xuhui District of Shanghai from 2013 to 2017. Methods The data from the Xuhui District Tuberculosis Management Information System, Disease Control Information Management Platform and electronic medical records of tuberculosis designated hospitals from 2013 to 2017 were collected. The data of diabetes management population were collected from the diabetes subsystem of Disease Control Information Management Platform. From 2013 to 2017. 1383 active tuberculosis patients were registered in Xuhui District of Shanghai, including 903 males and 480 females. Among them, there were 147 cases of diabetes complicated with pulmonary tuberculosis and 1236 cases of pulmonary tuberculosis only. The demographic data was derived from the statistical yearbook of Xuhui District. The clinical data of the two groups were compared and analyzed. Results From 2013 to 2017? 147 cases of diabetes mellitus complicated with pulmonary tuberculosis were registered in Xuhui District of Shanghai, accounting for 10.63%( 147/1383) of all registered pulmonary tuberculosis cases. The registered incidence of pulmonary tuberculosis in diabetic patients (54. 20/100 000-117. 18/100 000) was about 2. 18-4. 72 times that of the general population (22. 86/100 000 --28. 62/100 000). In the group of diabetes mellitus complicated with pulmonary tuberculosis patients, the average age was 64. 26+ 1. 06 years, the proportion of male patients was 81. 0%(119/147). the proportion of smear positive patients was 57. 1 %(84/147), the median patient delay time (quartile)(M(Q1 ,Q3)) was 14. 0 (5. 0,32. 0) days, and the average treatment course was 10. 90±2. 68 months. In the group of pulmonary tuberculosis only patients w the average age was 43. 75 zb 0. 59 years * the proportion of male patients was 63. 4%(784/1236), the proportion of smear positive patients was 37. 1 %(458/1236). the median patient delay time (quartile)(A4(Q .Q )) was 11.5 (2.0.27.0) days, and the average treatment course was 10. 09i3. 14 months. There were significant differences in these indicators (t=11.73, X^2 = 17. 80, X^2 =22. 25, Z=_2. 22,t= 3. 16, all Ps<0. 05). Conclusion The registration incidence rate of pulmonary tuberculosis in diabetes mellitus patients is higher than that in the general population. The average age, male ratio* smear positive ratio, patient delay time and treatment course of diabetes mellitus complicated with pulmonary tuberculosis patients are higher than those of pulmonary tuberculosis only patients.