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顺铂类抗癌药物的研究现状及发展方向 被引量:11

Research Status and Development Direction of Cisplatinum Anticancer Drugs
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摘要 顺铂类药物是目前用于化学治疗肿瘤的常用药物。由于其具有抗癌谱广、作用强、与多种抗肿瘤药有协同作用等特点,而广泛应用于各种恶性肿瘤的临床治疗。仍其収展历史出収,通迆查阅有关顺铂类抗癌药物的中英文文献、知名网站収布的相关信息及临床对癌症治疗中的相关数据信息,对顺铂类药物的开収、収展现状和抗癌作用机制迚行综述,并对其研究斱向迚行了展望。 Cisplatinum drugs are common drugs for chemical treatment of cancer. They have been widely used in clinical treatment of various malignant tumors owing to their advantages, such as broad spectrum anti-cancer activity,strong function, and good synergistic effect with a variety of antitumor drugs. In this paper, starting from the development history of cisplatinum drugs, through the inspection of the relevant cisplatinum anticancer drugs in both English and Chinese literatures, the well-known website released relevant information and data information in clinical for cancer treatment, the development status and mechanism of anticancer action of cisplatinum drugs were reviewed,and the research direction in the future was prospected.
作者 张伟娜 李春玱 海士坤 李云辉 马玉芹 田华 ZHANG Wei-na;LI Chun-ling;HAIShi-kun;LI Yun-hu;MA Tu-qin;TIAN Hua(Department of Public Subjects, Shangqiu Medical College, Henan Shangqiu 476100, China;College of Chemistry and Molecular Engineering, Zhengzhou University, Henan Zhengzhou 450001, China;College of Chemistry and Environmental Engineering, Changchun University of Science and Technology,Jilin Changchun 130022, China)
出处 《当代化工》 CAS 2019年第3期628-633,共6页 Contemporary Chemical Industry
基金 河南省科技发展计划项目 项目号:182102310611 河南省高等学校青年骨干教师培养计划项目 项目号:2017GGJS282 河南省博士后科研项目 商丘医学高等专科学校博士科研启动项目 项目号:BSJH001
关键词 顺铂 抗癌药物 抗癌机制 药物制剂 Cisplatinum Anticancer drugs Antitumor mechanism Pharmaceutical preparations
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