微小RNA(miRNA-1306-3p)在多发性硬化疾病中的表达
摘要
目的探讨miRNA-1306-3P在临床多发性硬化的表达及其临床意义。方法收集多发性硬化卒中患者60例,选取同期在医院健康体检者50名为对照组。采用实时荧光定量PCR(RT-PCR)技术检测患者血清中miRNA-1306-3P的表达。结果多发性硬化患者血清miRNA-1306-3P表达与对照组比较表达上调,差异有统计学意义(P<0.01)。结论多发性硬化患者血清中miRNA-1306-3P表达显著上升,可预测多发性硬化疾病的发生。
出处
《临床检验杂志（电子版）》
2019年第3期96-97,共2页
Clinical Laboratory Journal(Electronic Edition)
二级参考文献45
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共引文献6
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1袁梅,周成芳,汤永红,袁海军.急性缺血性脑卒中患者血清miRNA-335表达水平及临床意义[J].中国动脉硬化杂志,2015,23(6):589-593. 被引量：20
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2钟勇,裴颖皓,王俊,宫剑滨,江时森.血清microRNA对心肌桥的诊断价值[J].中国动脉硬化杂志,2013,21(7):614-618. 被引量：2
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6徐健,刘金龙,丁丽萍,江娇.血清miRNA-499-5p在缺血性脑卒中的表达及临床意义[J].临床医药文献电子杂志,2017,4(22). 被引量：2
