摘要
目的:分析我院儿童药物不良反应(ADR)的发生特点,为临床合理用药提供参考。方法:对我院2015年1月至2017年6月收集的108份儿童药物ADR进行分析、总结。结果:108例儿童ADR中,男62例(57.4%),女46例(42.6%);静脉给药者居多(94例,占87.04%);抗感染药物引起的ADR居首位,涉及19种抗感染药物共79例(73.14%),中成药4种共11例(10.18%);皮肤及其附件损害是ADR最主要的表现,共82例(75.93%)。结论:增强对药物不良反应的防范意识,加强不良反应监测,确保临床安全、有效、合理用药。
Objective: To analyze the occurrence characteristics of adverse drug reactions (ADR) in children from our hospital, so as to provide reference for the clinical rational drug use. Methods: Analysis and summary were conducted on 108 children with ADR collected from Jan. 2015 to Jun. 2017 in our hospital. Results: Of the 108 children with ADR, 62 were male (57.4%) and 46 were female (42.6%). Intravenous administration accounted for the majority (94 cases, 87.04%). ADR induced by anti-infective drugs ranked the first, involving 79 kinds of anti-infective drugs (73.14%), and 11 kinds of Chinese patent medicine (11.18%). Skin and its attachment damage were the most essential manifestations of ADR, totally 82 cases (75.93%). Conclusion: It is necessary to enhance the awareness of prevention of adverse drug reactions, strengthen the monitoring of adverse drug reactions, and ensure the safe, effective and rational use of drugs.
作者
周莉
时艳平
侯红丽
李小象
郝建华
Zhou Li;Shi Yanping;Hou Hongli;Li Xiaoxiang;Hao Jianhua(Kaifeng Children,’s Hospital, Henan Kaifeng 475000, China)
出处
《儿科药学杂志》
CAS
2019年第4期51-53,共3页
Journal of Pediatric Pharmacy
关键词
药物不良反应
儿童
合理用药
adverse drug reactions
children
rational drug use