温经止痛方治疗肺癌骨转移患者癌痛的临床观察

Clinical observation of Wen Jing Zhi Tong recipe in treating cancer pain in lung cancer with bone metastases

目的观察温经止痛方温敷背部经络对肺癌骨转移患者癌痛及生存质量的影响。方法 70例非小细胞肺癌伴骨转移合并中、重度癌痛患者,分为治疗组和对照组,治疗组35例,对照组35例。所有患者给予盐酸羟考酮缓释片止痛治疗,治疗组加温经止痛方温敷背部经络治疗,对照组加安慰剂外敷,观察两组疼痛数字评分(NRS)变化、止痛治疗起效时间、滴定时间,爆发痛,生存质量评分。结果两组治疗后NRS评分差异有统计学意义,治疗组疼痛的缓解优于对照组(P<0.05);治疗组与对照组比较,止痛治疗起效时间更短、滴定时间更短、爆发痛次数更少,两组差异有统计学意义(P<0.05);治疗后1个月治疗组较对照组生存质量评分更高,两组差异有统计学意义(P<0.05)。结论温经止痛方温敷背部经络可减轻肺癌骨转移癌痛,改善患者生存质量。

Objective The clinical effect of Wen Jing Zhi Tong recipe warming back meridians on cancer pain and quality of life in lung cancer with bone metastases.Methods A total of 70 patients diagnosed with lung cancer with bone metastases and suffering from moderate and severe cancer pain were randomly divided into the treatment group and the control group(n=35 for each).The patients in both groups were administered taking oxycodone hydrochloride prolonged-release tablets.On the basis of this,Wen Jing Zhi Tong recipe warming back meridians were given to patients in the treatment group,while the control group was given external application of placebo.NRS scores,onset time,titration time for analgesic drugs,breakthrough pain,quality of life were evaluated between the two groups.Results The difference of NRS scores between the two groups was statistically significant.The pain relief in the treatment group was better than that in the control group(P<0.05).The onset time,titration time for analgesic drugs,and breakthrough pain were significantly reduced in the treatment group when compared with the control group after treatment(P<0.05).The improvement on quality of life in the treatment group was more obviously than that in the control group after treatment for 1 month(P<0.05).Conclusion The therapy of Wen Jing Zhi Tong recipe can significantly improve the curative effect of cancer pain,and improve the quality of life of cancer pain patients.