膳食平衡指数与男性精液质量关系研究

The Relationship Between Dietary Balance Index and Semen Quality Among Men

目的:应用调整的膳食平衡指数-07 (dietary balance index,DBI-07)评价男性精液质量,探讨膳食平衡指数水平与生殖门诊就诊男性精液质量的关系,为生育男性的营养宣教及干预提供科学依据。方法:选取2016—2017年合肥市某三甲医院生殖中心门诊部就诊男性,使用食物频率问卷(FFQ)调查其膳食情况,使用DBI-07评价其膳食质量,并分析DBI-07与男性精液质量的关系。结果:膳食质量情况处于摄入不足、摄入过量以及膳食总体不平衡的状态。男性精液质量异常率为54. 93%,BMI、体力活动锻炼与男性精液质量有关。Logistic回归分析DBI-07各指标与男性精液质量的关系,调整了年龄、吸烟、BMI、饮酒、体力活动等混杂因素之后,结果表明,DBI-07-HBS是精子总数以及前向运动精子活动度异常的风险因素,OR值分别为2. 40 (95%CI∶1. 06～5. 43),2. 32 (95%CI∶1. 13～4. 35),差异有统计学意义(P=0. 035,0. 020)。另外,DBI-07-DQD会增加精子形态异常的风险,OR值为0. 39 (95%CI∶0. 16～0. 91),差异有统计学意义(P=0. 030)。结论:该人群膳食摄入的总体不平衡较为严重,DBI-07与男性精液质量有关,膳食摄入的过量以及不平衡会增加精液质量异常的风险。生育期男性要加强营养均衡,提高膳食质量。

【Objective】The adjusted dietary balance index-07(DBI-07)was applied to evaluate semen quality,and the relationship between dietary balance index and semen quality among men attempting fertility was discussed to provide scientific evidence for nutrition education and intervention in the future of male fertility.【Method】The study recruited males from the outpatient department of reproductive center of a third-grade first-class hospital in Hefei from 2016 to 2017.Food frequency questionnaire(FFQ)was used to investigate the dietary.The dietary quality was evaluated using the DBI-07 Scoring[Method].And we analyzed the relationship between DBI-07 and semen quality.【Result】The quality of dietary intake was not balanced and with a low/high dietary intake in generally.The abnormal rate of semen quality was 54.93%.BMI and physical activity exercise were related to semen quality in men.In the Logistic regression models,after additional adjusting for possible co-variables,such as age,BMI,smoking status,alcohol consumption and physical activity,DBI-07 was inversely related to semen quality.DBI-07-HBS was the risk factors for the decreased of sperm count and progressive motility.The odds ratio was 0.92(95%CI∶0.18~0.89),0.82(95%CI∶0.23~0.85),(P=0.026,0.015).In addition,DBI-07-DQD could increased the risk of abnormal sperm morphology.The odds ratio was 1.66(95%CI∶0.16~0.84),(P=0.017).【Conclusion】The overall imbalance of dietary intake is relatively serious.DBI-07 is related to male semen quality.Excessive dietary intake and dietary imbalance will increase the risk of abnormal semen quality.Men should strengthen the balance of nutrition and improve the diet quality.