计算机辅助药物设计用于化妆品植物源功效原料筛选的建议

Recommendation of computer-aided drug design for the screening of cosmetic plant source efficacy materials

对计算机辅助药物设计技术应用于化妆品植物来源功效物质筛选和预测进行综述,论述其应用于预测药用植物所含成分在皮肤相关生物学途径中靶蛋白的结合关系,以及整体评价药用植物在皮肤生理学上的作用。提出构建完整、高效、便捷的原料研发模式的建议,并对其进行展望。

The application of computer-aided drug design technology in the screening and prediction of functional substances in cosmetic plant materials was reviewed,its application in predicting the binding relationship of target proteins in skin-related biological pathways of medicinal plants,and the overall evaluation of the role of medicinal plants in skin physiology were discussed.Suggestions for constructing a complete,efficient and convenient raw material research and development model are proposed and prospected.