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鹅细小病毒灭活苗佐剂筛选研究 被引量:1

Study on adjuvant screening of inactivated goose parvovirus vaccine
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摘要 本研究以纯化后的番鸭源鹅细小病毒(GPV)现地分离株FB株-F7鸭胚培养毒株作为灭活苗研究种毒,接种12日龄鸭胚,获得较高滴度的鸭胚病毒液用于灭活疫苗的制备。灭活的病毒液半成品抗原分别用赛比克公司的Montanide ISA 71、Montanide ISA 201、MontanideISA 763、IMS 1313和复合佐剂5种佐剂制备了鹅细小病毒灭活疫苗,分别进行了雏番鸭安全性试验及免疫效果对比试验。通过对比不同佐剂小鹅瘟灭活疫苗的安全性及免疫效果,初步确认复合佐剂为鹅细小病毒FB-F7株灭活苗最佳免疫佐剂。
出处 《广东畜牧兽医科技》 2019年第2期33-35,共3页 Guangdong Journal of Animal and Veterinary Science
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