丙种球蛋白辅助盐酸氨溴索治疗新生儿肺炎的疗效研究

Gammaglobulin adjunctive effect of intravenous injection of ambroxol hydrochloride on neonatal pneumonia

目的:探讨丙种球蛋白辅助盐酸氨溴索静脉滴注对新生儿肺炎的影响。方法:将2016年1月～2018年12月收治的142例新生儿肺炎患儿作为研究对象,利用随机数字分组法将其分为研究组与对照组,各71例。给予对照组盐酸氨溴索静脉滴注治疗,研究组在对照组基础上辅以丙种球蛋白进行治疗。对比两组患儿临床治疗效果及肺功能情况。结果:研究组临床总有效率(95.77%)显著优于对照组,差异有统计学意义(87.32%),差异具有统计学意义(P<0.05);两组患儿肺功能指标较治疗前均显著改善(P<0.05),但研究组各项肺功能指标均显著优于对照组(P<0.05)。结论:丙种球蛋白辅助盐酸氨溴索治疗新生儿肺炎,可显著改善新生儿肺功能,提高临床治疗效果。

Objective To investigate the effect of intravenous injection of gamma globulin combined with ambroxol hydrochloride on neonatal pneumonia.Method 142 cases of neonatal pneumonia in our hospital from January 2016 to December 2018 were selected as the research object,and they were divided into study group(71 cases)and control group(71 cases)by random num-ber grouping method.The control group was given ambroxol hydrochloride intravenous drip therapy,and the study group was treated with gamma globulin on the basis of the control group.The clinical effect and pulmonary function of the two groups were compared.Results The total clinical effective rate of the study group(95.77%)was significantly higher than that of the control group(87.32%),and the difference was statistically significant(P<0.05);the tidal pulmonary function indexes of the two groups were significantly improved compared with those before treatment(P<0.05),but the pulmonary function indexes of the study group were significantly better than those of the control group(P<0.05).Conclusion Intravenous injection of gamma globulin and ambroxol acid can significantly improve neonatal pulmonary function and therapeutic effect.