高流量氧驱动口咽喷雾联合鼻腔滴注利多卡因在支气管镜检查中的应用

Application of high flow oxygen-driven oral spray and nasal inhalation lidocaine in bronchoscopy

目的观察及评价高流量氧驱动口咽喷雾联合鼻腔滴注利多卡因在支气管镜检查中的麻醉效果。方法将254例患者随机分为研究组和对照组,研究组患者在8L/min氧流量驱动下,喷雾麻醉口咽部联合鼻腔内滴注利多卡因表面麻醉,对照组采用常规雾化吸入利多卡因麻醉法,分别比较两组患者的视觉模拟评分法(visual analogue scale,VAS)、麻醉效果、术中追加麻药量、不同时点患者心率、血压、SpO_2及不良反应情况。结果研究组的麻醉效果优于对照组(P=0.013),研究组不良反应发生率(P=0.047)、VAS(P<0.001)、术中追加麻药量均低于对照组(P<0.001),研究组各时点的生命体征较对照组更平稳(P<0.05),以上各组间差异具有统计学意义。结论采用高流量氧口咽喷雾联合经鼻腔滴注利多卡因,较之雾化吸入法可提高表面麻醉效果,改善患者感受,值得临床推广使用。

Objective To observe and evaluate the anesthetic efficacy of high flow oxygen-driven oral spray and nasal inhalation lidocaine in bronchoscopy examination. Methods 254 patients undergoing bronchoscopy were randomly divided into two groups. The study group received surface anesthesia with 8L/min oxygen-driven oral spray and nasal inhalation idocaine, while the control group received nebulize lidocaine method. Their visual analogue scale (VAS), anesthesia effect, additional anesthetic dose, vital signs and adverse reactions were compared between the two groups. Results Compared with the control group, the anesthesia effect of the study group were better ( P =0.013). The incidence of adverse reactions ( P =0.047), VAS ( P< 0.001), and additional anesthetic dose ( P< 0.001) were lower in the study group than in the control group. The vital signs in the study group were more stable ( P< 0.05). Conclusion High flow oxygen-driven oral spray and nasal inhalation lidocaine can improve the effect of surface anesthesia and patient experience, which is worth of being widely generalized.