百次以上男性机采献血者铁营养状况研究

Study on iron stores of male platelet donors who donated more than one hundred times

目的调查百次以上男性机采献血者的血清铁蛋白(SF)、血红蛋白(Hb)水平情况。方法随机抽取本站百次以上男性机采献血者91例和初次男性献血者40例,检测其SF和Hb水平并统计分析。结果首次献血者与百次以上男性机采献血者Hb均值分别为143.9g/L和141.8g/L,中位数为143.5g/L和139.0g/L;差异有统计学意义(P<0.05)。首次献血者与百次以上男性机采献血者SF均值分别为66.6ng/mL和29.5ng/mL,中位数为65.5ng/mL和19.9ng/mL;差异有统计学意义(P<0.05)。百次以上男性机采献血者SF和Hb水平会随着总献血次数的增加而下降(SF与献血次数的Spearman相关系数-0.208,P=0.048,Hb与献血次数的Spearman相关系数-0.054,P=0.611)。结论百次以上男性机采献血者SF和Hb水平会随着献血总次数和频率的增加而逐渐减少,采血机构应该更加重视对高频多次机采献血者SF的检测和加强铁营养的宣传和指导。

Objective To investigate the serum ferritin(SF)and hemoglobin(Hb)levels in male platelet donors who donated more than one hundred times.Methods A total of 91 male platelet donors who donated more than one hundred times and 40 first-time male blood donors were randomLy selected.The contents of SF and Hb were detected and analyzed statistically.Results The mean Hb values of the first-time male blood donors and male platelet donors who donated more than one hundred times were 143.9 g/L and 141.8 g/L respectively,the median was 143.5 g/L and 139.0 g/L,the difference was statistically significant(P<0.05).The SF means were 66.6 g/L and 29.5 g/L respectively,the medians were 65.5 g/L and 19.9 g/L,the difference was statistically significant(P<0.05).SF and Hb levels of male platelet donors who donated more than one hundred times decreased with the increase of total blood donation times(Spearman correlation coefficient of SF and blood donation frequency was-0.208,P=0.048,Spearman correlation coefficient of hemoglobin and blood donation times was-0.054,P=0.611).Conclusion The SF level of male platelet donors who donated more than one hundred times will gradually decrease with the increase of the number of blood donation.Blood collection agencies should pay more attention to the detection of SF and strengthen the publicity and guidance of iron nutrition.