秦皇岛地区1型糖尿病儿童及青少年生存质量影响因素研究

Quality of life in children and adolescents with type 1 diabetes mellitus in Qinhuangdao

目的探讨秦皇岛地区1型糖尿病儿童及青少年的生存质量影响因素。方法选取2015年1月～2018年6月于秦皇岛第一医院以及秦皇岛辖区各区县级医院就诊的1型糖尿病儿童及青少年110例作为观察组,同时选取健康儿童及青少年110名作为对照组。采用儿童生存质量测定量表评估两组生存质量。结果观察组生理功能、情感功能、社会功能、学校功能得分及总分明显低于对照组,差异均有统计学意义(P <0.05);父母分居或离异、母亲初中文化以下、父亲初中文化以下、非独生子女的患儿生存质量不良率明显高于父母已婚或同居、母亲初中文化以上、父亲初中文化以上、独生子女的患儿,差异均有统计学意义(P <0.05);Logistic回归分析结果显示:父母分居或离异、非独生子女是1型糖尿病儿童及青少年生存质量的危险因素(OR=2.489、1.988,P <0.05),母亲文化程度初中及以上是1型糖尿病儿童及青少年生存质量的保护因素(OR=0.800,P <0.05)。结论秦皇岛地区1型糖尿病儿童及青少年的生存质量与父母婚姻状况、是否独生子女及母亲文化程度有关。

Objective To explore the influencing factors of quality of life of children and adolescents with type 1 diabetes mellitus in Qinhuangdao area. Methods A total of 110 children and adolescents with type 1 diabetes who were enrolled in the First Hospital of Qinhuangdao and county-level hospital in Qinhuangdao from January 2015 to June 2018 were selected as observation group, while 110 healthy children and adolescents were selected as control group. The qualities of life of the two groups were assessed by the Pediatric Quality of Life Inventory Measurement Models. Results The scores of physiological function, emotional function, social function, school function and total score of the observation group were significantly lower than those of the control group, and the differences were statistically significant (P < 0.05). The rates of poor quality of life in parents separated or divorced, mother junior high school culture below, father junior high school culture below, and non-only children were significantly higher than those of parents who were married or cohabited, mother junior high school culture above, father junior middle school culture above, and only one children (P < 0.05). Logistic regression analysis showed that parents′ separation or divorce and non-only children were risk factors for the quality of life of children and adolescents with type 1 diabetes mellitus (OR = 2.489, 1.988, P < 0.05), and the mother′s educational level in junior middle school and above was the protective factor for the quality of life of children and adolescents with type 1 diabetes mellitus (OR = 0.800, P < 0.05). Conclusion The quality of life of children and adolescents with type 1 diabetes in Qinhuangdao area are related to their parents′marital status, whether they have only one child or not and their mother′s educational level.