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子痫前期患者检测血清25-羟基维生素D_3的临床价值分析 被引量:3

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摘要 目的探讨检测子痫前期患者血清25-羟基维生素D_3[25(OH)D_3]水平的临床价值。方法 100例孕妇作为研究对象,以实验室指标和妊娠结局作为依据分为妊娠期高血压组(30例)、轻度子痫前期组(20例)、重度子痫前期组(20例)、正常妊娠组(30例)。检测各组孕妇的血清25(OH)D_3水平,并进行比较。结果妊娠期高血压组与正常妊娠组的血清25(OH)D_3水平分别为(18.56±2.83)、(19.11±3.25)ng/ml,两组比较差异无统计学意义(t=0.6990, P=0.4873>0.05)。轻度子痫前期组和重度子痫前期组孕妇的血清25(OH)D_3水平分别为(13.02±1.26)、(8.88±0.64)ng/ml,均明显低于妊娠期高血压组和正常妊娠组孕妇,差异均有统计学意义(P<0.05)。重度子痫前期组的血清25(OH)D_3水平明显低于轻度子痫前期组,差异有统计学意义(t=13.1010, P=0.0000<0.05)。结论低水平的血清25(OH)D_3水平与子痫前期患者发病具有一定的相关性,可对子痫前期的发生和发展进行预测。
出处 《中国现代药物应用》 2019年第7期49-50,共2页 Chinese Journal of Modern Drug Application
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