金虎退黄汤治疗湿瘀互结型胆汁淤积性肝病临床观察

Clinical observation of Jinhu Tuihuang decoction in the treatment of damp-stasis type of cholestatic liver disease

目的探讨金虎退黄汤治疗湿瘀互结型胆汁淤积性肝病临床效果。方法 87例湿瘀互结型胆汁淤积性肝病患者,根据治疗方式不同分为治疗组(44例)和对照组(43例)。对照组患儿仅使用丁二磺酸腺甘蛋氨酸和熊去氧胆酸胶囊治疗,治疗组患者在对照组基础上加用金虎退黄汤治疗。比较两组患者的临床疗效及治疗前后的症状积分。结果治疗组患者显效28例、有效13例、无效3例,总有效率为93.18%;对照组患者显效12例、有效21例、无效10例,总有效率为76.74%。两组总有效率比较差异有统计学意义(χ~2=4.623, P<0.05)。治疗后,治疗组症状积分为(3.17±0.89)分,对照组治疗后为(6.27±0.96)分,治疗组低于对照组,差异有统计学意义(t=15.624, P<0.05)。结论金虎退黄汤治疗湿瘀互结型胆汁淤积性肝病有着良好的临床疗效,可以改善患者临床症状,值得在临床中推广。

Objective To discuss the clinical effect of Jinhu Tuihuang decoction in the treatment of damp-stasis type of cholestatic liver disease.Methods A total of 87 patients with damp-stasis type of cholestatic liver disease were divided by different treatment methods into treatment group(44 cases)and control group(43 cases).The control group was treated with glycosyl methionine and ursodeoxycholic acid capsules,and the treatment group was treated with Jinhu Tuihuang decoction on the basis of the control group.The clinical efficacy and symptom score before and after treatment in two groups was compared.Results The treatment group had 28 excellent cases,13 effective cases and 3 ineffective cases,with total effective rate as 93.18%,while the control group had 12 excellent cases,21 effective cases and 10 ineffective cases,with total effective rate as 76.74%.Both groups had no statistically significant in total effective rate(χ^2=4.623,P<0.05).After treatment,the treatment group had symptom score as(3.17±0.89)points,which was(6.27±0.96)points in the control group.the treatment group was lower than the control group,and the difference was statistically significant(t=15.624,P<0.05).Conclusion Jinhu Tuihuang decoction shows good clinical efficacy in treating damp-stasis type of cholestatic liver disease.It can improve the clinical symptoms of patients and is worth clinical promoting.