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盐酸右美托咪定在小儿骶麻镇静中的应用价值及对患儿应激反应的影响 被引量:1

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摘要 目的评价盐酸右美托咪定在小儿骶麻镇静中的应用价值及对患儿应激反应的影响。方法选取我院收治的拟行下腹部以下手术治疗的患儿60例,随机分为观察组和对照组,各30例,分别采用盐酸右美托咪定和丙泊酚辅助镇静。观察两组患儿麻醉前及麻醉20 min后心率(HR)、平均动脉压(MAP)等基础生命指标以及血糖、皮质醇、肾上腺素浓度等应激反应指标变化;比较两组手术时间、术后苏醒时间以及术后不良反应发生率。结果麻醉前,两组患儿HR和MAP比较,差异无统计学意义(P>0.05);麻醉20 min后,观察组患儿HR、MAP水平均低于对照组(P<0.01)。给药前两组患儿血糖、皮质醇和肾上腺素浓度比较,差异不显著(P>0.05);麻醉20 min后,观察组患儿血糖、皮质醇和肾上腺素浓度均低于对照组(P<0.01)。观察组手术时间和术后苏醒时间均短于对照组(P<0.01),术后不良反应发生率低于对照组(P<0.05)。结论在小儿骶麻镇静中辅助应用盐酸右美托咪定,能够有效稳定患儿生命体征,降低应激反应,减少不良反应,值得临床推广应用。
出处 《白求恩医学杂志》 2018年第6期588-589,共2页 Journal of Bethune Medical Science
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