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H型高血压患者脂联素及肿瘤坏死因子-α水平变化的分析 被引量:1

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摘要 目的观察H型高血压患者血清脂联素(ADPN)和肿瘤坏死因子-α(TNF-α)水平变化,并探讨ADPN和TNF-α在不同血压等级的水平变化。方法 2017年1—12月丽水市中医院收治的原发性高血压患者92例,将H型高血压患者65例设为H型高血压组,将非H型高血压27例设为高血压对照组,并选取同时期健康人群30例设为健康组。检测三组血清同型半胱氨酸(Hcy)、ADPN及TNF-α水平。结果 TNF-α水平H型高血压组最高,其次为高血压对照组,两组均远高于健康组,差异有统计学意义(P<0.05)。ADPN水平H型高血压组略低于高血压对照组,两组均远低于健康组,差异有统计学意义(P<0.05)。无论是H型高血压组还是高血压对照组,随高血压等级的增加,TNF-α水平呈上升趋势,ADPN水平呈下降趋势。结论 H型高血压患者的血清ADPN水平降低、TNF-α水平增高,且ADPN和TNF-α水平与血压等级高低有关。
出处 《中国乡村医药》 2019年第8期25-26,共2页
基金 浙江省中医药科技计划项目(2016ZA208)
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