子宫内膜异位症与卵巢癌关系的研究进展

Research Progress on the Relationship between Endometriosis and Ovarian Cancer

子宫内膜异位症(endometriosis,EMs)是一种良性妇科疾病,但具有恶性行为。流行病学及病理学等研究证实EMs可增加卵巢癌,尤其是透明细胞癌和子宫内膜样癌的风险。近年国内外关于EMs相关卵巢癌(endometriosis associated ovarian cancer,EAOC)的报道不断增加,已证实这是一类特定类型的卵巢癌,EAOC的病因、发病机制和临床特点的研究已成为热点。通过阅读大量文献,分析目前报道的EAOC的危险因素、发病机制、临床特点及诊断方法,以提高对该病的认识。

Endometriosis (EMs) is a benign gynecological disease with malignant behavior. Epidemiological and pathological studies have confirmed that EMs can increase the risk of ovarian cancer, especially clear cell cancer and endometrioid cancer. In recent years, reports on endometriosis associated ovarian cancer (EAOC) have been increasing both at home and abroad. Researches have confirmed that EAOC is a specific type of ovarian cancer. The research on the etiology, pathogenesis and clinical characteristics of EAOC has become a hot spot. Through reading a large number of literatures, this paper analyzed the risk factors, pathogenesis, clinical characteristics and diagnostic methods of EAOC reported so as to improve the understanding of the disease.