HPV阴性宫颈胃型腺癌一例并文献复习

HPV-Negative Gastric Type Adenocarcinoma of the Uterine Cervix:A Case Report

宫颈胃型腺癌(GAS)是一类罕见的宫颈黏液腺癌,通常与人乳头瘤病毒(HPV)感染无关,但其具体发病机制尚不明确。GAS恶性程度较高,病程进展快,临床表现不具有特异性,预后较差。相对于其他常见的宫颈恶性肿瘤,其筛查手段更为有限,早期诊断更为困难。回顾性分析吉林大学第二医院收治的1例GAS患者的诊治过程,并复习相关文献,分析其临床特点,以提高临床医生对该疾病的诊治水平。

Gastric type adenocarcinoma of the uterine cervix (GAS) is a rare subtype of cervical mucinous adenocarcinoma and is usually unrelated to human papillomavirus (HPV) infection. However, its specific pathogenesis is still unclear. GAS is a disease with high malignancy, fast progression, no specific clinical manifestations and poor prognosis. Compared with other common cervical malignancies, screening methods are more limited, and early diagnosis is more difficult. A retrospective analysis of the diagnosis and treatment of a patient with GAS admitted to the Second Hospital of Jilin University, and relevant literature had been reviewed to analyze its clinical features to improve the diagnosis and treatment of clinicians.