米索前列醇片在足月妊娠引产中的应用

Application of Misoprostol Tablets in the Induction of Labor in Full-term Pregnancy

目的:观察米索前列醇片在足月妊娠引产中的应用效果。方法:选取2017年8月至2018年8月期间在我院住院并有引产指征的160例患者为研究对象,按随机数表法将患者分为观察组及对照组各80例,对照组采用催产素引产,观察组应用小剂量米索前列醇片引产,观察两组患者引产效果、各产程时间、剖宫产率、新生儿窒息发生率和胎心异常、羊水污染、巨大儿发生率。结果:观察组产妇引产有效率、胎心异常、羊水污染、新生儿窒息、巨大儿发生率与对照组相比无统计学意义(P>0.05);观察组产妇第一产程、第二产程、总产程时间、剖宫产率显著少于对照组,差异具有统计学意义(P<0.05)。结论:米索前列醇片用于足月妊娠引产是有效安全的,可缩短产程,降低剖宫产率。

Objective: To observe the effect of Misoprostol tablets in induction of labor of full-term pregnancy. Methods: From August 2017 to August 2018, 160 patients with indications of induced labor in our hospital were selected as the research objects. The patients were divided into observation group and control group according to random number table. The control group was induced by oxytocin, while the observation group was induced by low-dose Misoprostol tablets. The induction effect, duration of labor, cesarean section rate, incidence of neonatal asphyxia and fetus, cardiac abnormalities, amniotic fluid contamination and incidence of macrosomia of the two groups were observed. Results: There was no significant difference in the rate of induction of labor, abnormal fetal heart rate, amniotic fluid contamination, neonatal asphyxia, and macrosomia in the observation group compared with the control group (P>0.05). The first stage of labor, the second stage of labor, and the total stage of labor were observed in the observation group. The time and cesarean section rate were significantly lower than the control group, and the difference was statistically significant (P<0.05). Conclusion: Misoprostol tablets are effective and safe for induced labor of full-term pregnancy, which can shorten the labor process and reduce the rate of cesarean section.