醒脑静联合盐酸法舒地尔在高血压脑出血术后的效果分析

Effect of Xingnaojing combined with fasudil Hydrochloride on postoperative hypertensive intracerebral Hemorrhage

目的探究醒脑静联合盐酸法舒地尔在高血压脑出血术后的效果。方法选取2017年4月至2018年6月在本院接受治疗的高血压脑出血患者74例,采用随机数字表法将其分为观察组和对照组,每组37例患者,对照组患者在常规治疗的基础上采用醒脑静注射液进行静脉滴注治疗,观察组在对照组的基础上采用醒脑静注射液联合盐酸法舒地尔注射液静脉滴注治疗,对比两组患者术后并发症的发生率、病死率、治疗效果和生活质量。结果观察组的并发症发生率为2.7%,对照组为21.6%,观察组显著低于对照组(P<0.05),观察组的病死率为2.7%,对照组为24.3%,观察组明显低于对照组(P<0.05),观察组患者的治疗有效率为97.3%,对照组为72.9%,观察组显著高于对照组,两组差异具有统计学意义(P<0.05)。观察组的生活质量总评分为(89.1±16.5)分,对照组(71.7±12.5)分,观察组显著高于对照组,两组差异具有统计学意义(P<0.05)。结论醒脑静联合盐酸法舒地尔在高血压脑出血术后的效果显著,可以降低其手术并发症的发生率,降低患者病死率,提高治疗的有效率,改善患者的生活质量,整体提升治疗效果,建议临床上进一步推广。

Objective To investigate the effect of Xingnaojing combined with fasudil hydrochloride on postoperative hypertensive intracerebral hemorrhage. Methods From April 2017 to June 2018, 74 patients with hypertensive intracerebral hemorrhage who were treated in our hospital were divided into observation group (n=37) and control group (n=37). Patients in the control group were treated by intravenous drip with Xingnaojing injection on the basis of routine treatment, while those in the observation group were treated with xingnaojing injection combined with fasudil hydrochloride intravenous drip on the basis of the control group. The incidence, mortality, therapeutic effect and quality of life were compared between the two groups. The incidence of complications in the observation group was 2.7% and that in the control group was 21.6%. It was significantly lower in the observation group than in the control group (P<0.05). The mortality was 2.7% in the observation group and 24.3% in the control group. The effective rate of treatment was 97.3% in the observation group and 72.9% in the control group, which was significantly higher in the observation group than in the control group (P<0.05). The difference between the two groups was statistically significant (P<0.05). The total score of quality of life was (89.1±16.5) in the observation group and (71.7±12.5) in the control group, which was significantly higher in the observation group than in the control group. The difference between the two groups was statistically significant (P<0.05). Conclusion Xingnaojing combined with fasudil hydrochloride has a significant effect on postoperative hypertensive intracerebral hemorrhage. It can reduce the incidence of operative complications, reduce the mortality of patients, improve the effective rate of treatment and improve the quality of life of the patients. It is suggested that the treatment should be further popularized clinically.