纳洛酮联合无创呼吸机治疗老年慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭的临床疗效分析

Clinical analysis of naloxone combined with noninvasive ventilator in the treatment of senile chronic obstructive pulmonary disease with type II respiratory failure

目的研究老年慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭患者临床治疗中应用纳洛酮联合无创呼吸机的效果。方法回顾性分析2015年1月至2017年1月本院老年慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭患者94例,依据治疗方法分为观察组、对照组各47例,观察组接受纳洛酮联合无创呼吸机治疗,对照组仅接受无创呼吸机治疗,比较两组效果。结果观察组治疗总有效率为93.62%,对照组76.60%;观察组治疗后PaO_2、PaCO_2、pH水平均优于对照组(P<0.05)。结论纳洛酮联合无创呼吸机治疗老年慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭能够更迅速有效改善患者临床症状,改善患者血气指标水平,可推广。

Objective To study the effect of naloxone combined with non-invasive ventilator in elderly patients with chronic obstructive pulmonary disease and type Ⅱ respiratory failure. Methods A retrospective analysis of 94 elderly patients with type Ⅱ respiratory failure from January 2015 to January 2017 in our hospital was performed and divided into observation group (n=47) and control group (n=47). The observation group was treated with naloxone combined with non-invasive ventilator, while the control group was only treated with non-invasive ventilator. Results The total effective rate of treatment in the observation group was 93.62% and that in the control group was 76.60%. The level of PaO2, PaCO2, pH in the observation group was better than that in the control group (P<0.05). Conclusion Naloxone combined with noninvasive ventilator in the treatment of senile chronic obstructive pulmonary disease with type Ⅱ respiratory failure can improve the clinical symptoms and blood gas index more quickly and effectively.