生脉注射液对老年患者LC围术期血流动力学的影响

Effect of Shengmai injection on perioperative hemodynamics in elderly patients undergoing LC

目的探讨生脉注射液对行腹腔镜胆囊切除术(LC)的老年患者血流动力学的影响。方法将我院收治的156例行LC的老年患者按随机抽签法分为观察组和对照组,各78例。两组均实施静吸复合全麻,同时观察组麻醉前24 h和30 min均静脉注射40～60 m L生脉注射液。比较两组不同时间血流动力学指标。结果 T1～T5时,两组MAP水平均随时间变化而出现波动(P<0.01);T2～T5时,观察组MAP水平低于对照组(P<0.05)。T1～T5时,两组HR、SV及CO水平均无明显波动,且组间无显著差异(P>0.05)。结论生脉注射液对老年患者LC围术期血压具有稳定作用,且安全性高,可作为预防心脑血管意外的手段之一。

Objective To investigate the effect of Shengmai injection on hemodynamics in elderly patients undergoing laparoscopic cholecystectomy(LC). Methods A total of 156 elderly patients undergoing LC in our hospital were divided into observation group and control group by random lottery method, with 78 cases in each group. Both groups were given intravenous inhalation combined with general anesthesia, while the observation group received 40-60 mL Shengmai injection at 24 h and 30 min before anesthesia. The hemodynamic parameters at different time between the two groups were compared. Results At T1-T5, the MAP levels of both groups fluctuated with time(P<0.01);at T2-T5, the MAP levels of the observation group were lower than those of the control group(P<0.05). At T1-T5, the levels of HR, SV and CO of both groups did not fluctuate significantly, and there were no significant differences between the two groups(P >0.05). Conclusion Shengmai injection can stabilize the blood pressure of elderly patients undergoing LC during perioperative period, and has high safety, which can be used as one of the means to prevent cardiovascular and cerebrovascular accidents.