B族链球菌快速抗原检测在产前筛查中的应用价值

Application value of group B streptococcus rapid antigen detection in prenatal screening

目的探讨B族链球菌(GBS)快速抗原检测在产前筛查中的应用价值。方法将云浮市中医院2017年12月至2018年5月期间收治的68例孕晚期孕妇根据GBS快速抗原检测结果分为阴性组与阳性组,比较两组产妇妊娠结局和新生儿结局。结果 68例孕妇GBS快速抗原检测阴性率为88.2%(60/68)、阳性率为11.8%(8/68);阳性组妊娠不良结局发生率为62.5%,高于阴性组的18.3%,差异具有统计学意义(P<0.05);阳性组新生儿不良结局发生率为50.0%,高于阴性组的10.0%,差异具有统计学意义(P<0.05)。结论妊娠晚期感染GBS与妊娠结局及新生儿不良结局密切相关,GBS快速抗原检测快捷简便,准确率高,早期诊断可有效预防妊娠不良结局的发生。

Objective To explore the application value of group B streptococcus(GBS) rapid antigen detection in prenatal screening. Methods A total of 68 pregnant women in the third trimester of pregnancy who were admitted to Yunfu Hospital of Traditional Chinese Medicine during December 2017 and May 2018 were divided into negative group and positive group, according to the results of GBS rapid antigen test, then the pregnancy outcome and neonatal outcome were compared between the two groups. Results In 68 pregnant women, the negative rate of GBS rapid antigen test detection was 88.2%(60/68), and the positive rate was 11.8%(8/68). The incidence of adverse outcome of pregnancy in the positive group was 62.5%, which was significantly higher than 18.3% in the negative group(P<0.05). The incidence of adverse neonatal outcome in the positive group was 50.0%, which was significantly higher than 10.0% in the negative group(P<0.05). Conclusion GBS infection in the third trimester of pregnancy is closely related to pregnancy outcomes and adverse neonatal outcomes. GBS rapid antigen detection is quick and easy, and the accuracy is high. Early diagnosis can effectively prevent the occurrence of adverse pregnancy outcomes.