乳管镜、B超引导下麦默通微创旋切术治疗乳腺导管内肿物的效果及安全性研究

Study on the effect and safety of minimally invasive Mammotome biopsy system in the treatment of breast ductal mass guided by ductoscopy and B-ultrasound

目的研究与观察乳管镜、B超引导下麦默通微创旋切术用于乳腺导管内肿物的效果及安全性。方法选取2014年6月—2017年12月期间本院收治的103例乳腺导管内肿物患者为研究对象,将其随机分为对照组56例和实验组47例。对照组进行传统手术治疗,实验组则采用乳管镜、B超引导下微创旋切术进行治疗。统计与比较两组的手术时间、病灶组织切除重量、病灶切除准确率、出血量、切口愈合时间、并发症发生率、术后24h和48h的VAS评分及围术期应激指标(Cor、Ang-Ⅱ及β-EP)。结果实验组中不同病灶直径者的平均手术时间短于对照组,平均切除组织重量少于对照组,出血量小于对照组,切口愈合时间短于对照组,术后24h和48h的VAS评分重度疼痛率均低于对照组,术后应激指标均低于对照组,差异均有统计学意义(P均<0.05)。结论乳管镜、B超引导下微创旋切乳腺导管内肿物的效果较好,且安全性较高,在乳腺导管内肿物患者中的应用价值较高。

Objective To study and observe the effect and safety of minimally invasive Mammotome biopsy system in breast ductal mass guided by ductoscopy and B-ultrasound.Methods A total of 103 patients with breast ductal mass cared at our hospital from June 2014 to December 2017 were selected for the study,and they were randomly divided into a control group ( n =56) and an experimental group ( n =47).Patients in the control group were treated with traditional surgery,and patients in the experimental group were treated with minimally invasive Mammotome biopsy system guided by ductoscopy and B-ultrasound.Then the operation time,weight of removed lesion tissue,accurate rate of lesion excision,blood loss,time of incisional wound healing,incidence of complications,Visual Analogue Pain Scale (VAS) score at 24 hour and 48 hour after operation and perioperative stress indexes (Cor,Ang-Ⅱ and β-EP) of two groups were analyzed and compared.Results Patients with different lesion diameters in the experimental group had shorter mean operation time than those in the control group,the experimental group had lower mean weight of removed lesion tissues than the control group,the experimental group had less blood loss than the control group,the experimental group had shorter time of incisional wound healing than the control group,both of the post-operative 24 hour and 48 hour VAS scores in the experimental group yielded lower severe pain rates than those of the control group,and the experimental group had lower stress indexes after the operation than the control group,there were all statistically significant differences (allP<0.05).Conclusion The effect of minimally invasive Mammotome biopsy system guided by ductoscopy and B-ultrasound in the treatment of patients with breast ductal mass is better,and the safety is higher,so its application value for the patients with breast ductal mass is higher.