乳腺癌保乳手术与改良根治术治疗早期乳腺癌的疗效及生活质量比较

Comparison of curative effect and quality of life in early breast cancer treated with breast-conserving surgery and modified radical mastectomy for early breast cancer

目的比较乳腺癌保乳手术与改良根治术治疗早期乳腺癌的疗效及生活质量。方法选取2017年12月～2018年12月间我院行手术治疗的乳腺癌患者64例,根据手术方法不同分为两组,保乳组共32例,采取乳腺癌保乳手术,对照组共32例,采取改良根治术。比较两组的手术时间、住院时间及术中出血量、乳房外观效果和并发症及生活质量改善情况。结果两组患者均手术顺利,保乳组的手术时间、住院时间均短于对照组,保乳组的术中出血量显著少于对照组,保乳组乳房外观的优良率显著高于对照组,保乳组患者的手术并发症少于对照组,生活质量各项评分高于对照组,差异具有显著性(P<0.05)。结论在严格掌握保乳手术的适应证前提下,保乳手术治疗早期乳腺癌较改良根治术具有创伤小、并发症少、美观效果好等优点,且能显著提高患者的生活质量水平,值得广泛推广和应用。

Objective To compare the efficacy and quality of life of breast cancer breast-conserving surgery and modified radical mastectomy in treatment of early breast cancer.Methods A total of 64 breast cancer patients who underwent surgery in our hospital from December 2017 to December 2018 were enrolled.According to different surgical methods,the patients were divided into two groups.32 cases in the breast-preserving group were treated with breast-conserving surgery for early breast cancer.32 cases in the control group were treated with modified radical mastectomy.The operation time,hospitalization time and intraoperative blood loss,breast appearance effect and complications,and quality of life improvement were compared between the two groups.Results The operation was successful in both groups.The operation time and the hospitalization time of the breast-preserving group was shorter than that of the control group.The intraoperative blood loss of the breast-preserving group was significantly less than that in the control group.The excellent good rate of breast appearance in the breast-preserving group was significantly higher than that of the control group.The operative complications of the patients in the breast-preserving group were less than those of the control group,and the quality of life scores in the breast-preserving group were higher than those of the control group,and the difference was significant(P<0.05).Conclusion Under the premise of strict indications for breast-conserving surgery,breast-conserving surgery for early breast cancer has the advantages of less trauma,less complications,better aesthetic effect,and can significantly improve the quality of life of patients,which is worthy of promotion and application.