自主神经再平衡与心力衰竭

Autonomic rebalance and heart failure

心力衰竭(简称心衰)是许多心脏疾病发展的最终、最严重的临床表现,神经激素激活和自主神经失衡(交感神经兴奋性增强、迷走神经张力降低)是其重要的病理生理特征。通过对自主神经系统的干预实现自主神经再平衡有望改变心衰的历史进程,有可能成为治疗心衰的新途径。

Heart failure(HF) is the ultimate and most serious clinical manifestation of many heart diseases. The activation of neurohormone and the imbalance of autonomic nerve(enhanced sympathetic excitability and decreased vagal tone) are important pathophysiological features. The rebalance of autonomic nervous system through the intervention of autonomic nervous system is expected to change the historical process of heart failure, which may become a new way to treat heart failure.