黄体酮治疗黄体功能不全所致的先兆流产的疗效

Clinical Effect of Progesterone Therapy on Threatened Abortion caused by Luteal Insufficiency

目的:探究黄体功能不全致先兆流产患者行黄体酮治疗的临床效果。方法:择取2018年1月～2018年12月期间某院妇产科收治的98例黄体功能不全致先兆流产患者,根据患者入院时间先后顺序分为对照组49例和观察组49例。对照组患者行常规对症治疗,观察组患者行黄体酮治疗,对比两组患者保胎成功率、不良反应发生率、治疗前后人绒毛膜促性腺激素水平(HCG)以及患者临床症状消除时间。结果:治疗前两组患者HCG水平差异无统计学意义(P>0.05),治疗后观察组患者保胎成功率、不良反应、HCG水平和临床症状消退时间均优于对照组,差异有统计学意义(P<0.05)。结论:黄体功能不全致先兆流产患者行黄体酮效果理想,值得在临床中进行推广应用。

Objective:To explore the clinical effect of progesterone therapy on threatened abortion caused by luteal insufficiency.Methods:98 cases of threatened abortion due to luteal insufficiency admitted in a hospital from January 2018 to December 2018 were selected.According to the time of admission,the patients were divided into control group (49 cases) and observation group (49 cases).Patients in the control group received routine symptomatic treatment,while patients in the observation group received progesterone treatment.The success rate of fetal protection,the incidence of adverse reactions,the level of human chorionic gonadotropin (HCG) before and after treatment and the elimination time of clinical symptoms were compared between the two groups.Results:There was no significant difference in HCG level between the two groups before treatment ( P >0.05).After treatment,the success rate of fetal protection,adverse reactions,HCG level and time for clinical symptoms to subside of the observation group were better than those of the control group,and the difference was statistically significant ( P <0.05).Conclusion:The effect of progesterone on threatened abortion caused by luteal insufficiency is ideal,and it is worth popularizing in clinical practice.