免疫分析技术在“新型瘦肉精”残留检测中的应用

Application of immunoassay technique in detecting new type lean meat powder residues

近年来,一些"新型瘦肉精"药物被非法用于畜禽养殖,如苯乙醇胺A、赛庚啶、可乐定等,该类药物添加在饲料和动物饮水中能有效促进禽畜生长,提高瘦肉率,降低养殖成本,但其在肉制品中的残留会对人体产生蓄积毒性。免疫分析技术利用高亲和力抗体对抗原进行特异识别,灵敏度高,是目前快速检测方法研究的热点之一,已在"传统瘦肉精"的快速检测中成熟应用,但其在"新型瘦肉精"快速检测中的应用仍处于起步阶段。该文对免疫分析技术在"新型瘦肉精"残留检测中的应用进行综述,并对其未来发展方向进行展望。

In recent years,some new types of lean meat powder are used illegally for livestock and poultry breeding,such as phenylethanolamine A,cyproheptadine,clonidine etc. These drugs added in animal feeds and drinking water can effectively promote the growth of livestock,improve the ratio of lean meat,and reduce the production cost.However,their residues in meat products could accumulate in human bodies and generate cumulative toxicity. Immunoassay technology uses high affinity antibodies to recognize antigen specifically and with high sensitivity. At present,it is one of the hot spots in fast detection methods. It has been used in rapid detection of traditional lean meat powder,but its application in detecting new lean meat powder is still in its infancy. In this paper,using immunoassay technique to detect new lean meat powder residues was reviewed,and its future development direction was prospected.