水生生物启发的医用粘合剂的研究进展

Advances in aquatic bio-inspired medical adhesives

近年来,由于外科手术数量的急剧上升,临床上对能够在血液或者组织液等湿润环境中发挥黏附止血作用的医用粘合剂需求显著增加。随着对水生生物自然黏附机制和关键要素认识的不断深入,许多研究通过模仿生物黏附过程或者利用其作用官能团,开发了多种医用粘合剂。本文将从水生生物章鱼、贻贝启发的仿生医用粘合剂的分类、粘合机制、用途、临床应用进展及发展前景进行概述。

In recent years,due to the dramatic increase in the number of surgical operations,there has been a clinically significant increase in the demand for medical adhesives capable of cohesion in a moist environment that can overcome blood or tissue fluids in vivo.As the understanding of the mechanisms and key elements of natural adhesion to aquatic organisms continues to develop,a variety of medical adhesives have been developed by mimicking adhesion procedures or utilizing key functional groups.This article will review the classification,adhesion mechanism,use,research progress and development prospects of biomedical adhesives inspired by aquatic organisms octopus and mussels.