摘要
Fragranced products are wildly used in our daily life. However, their storage, application and quality are severely influenced by their strong volatility. In order to overcome these natural defects of fragrances,fragrance encapsulation approaches have been developed recently. In this study, a mild, simple and lowcost method of fragrance encapsulation was invented. Liposomes composed of soya lecithin/DSPEPEG2000/PLGA were prepared to encapsulate lily fragrance(LF). And these nanosized fragrance products was named LF-NPs. The hydrodynamic diameters of LF-NPs were approximately 100 nm and their encapsulation efficiency was up to 21.9%. Besides, LF-NPs could also prolong the release time of lily fragrance. Finally, the cytotoxicity tests indicated that LF-NPs offered biocompatibility. Therefore, LF-NPs were expected to have application prospects.
Fragranced products are wildly used in our daily life. However, their storage, application and quality are severely influenced by their strong volatility. In order to overcome these natural defects of fragrances,fragrance encapsulation approaches have been developed recently. In this study, a mild, simple and lowcost method of fragrance encapsulation was invented. Liposomes composed of soya lecithin/DSPEPEG2000/PLGA were prepared to encapsulate lily fragrance(LF). And these nanosized fragrance products was named LF-NPs. The hydrodynamic diameters of LF-NPs were approximately 100 nm and their encapsulation efficiency was up to 21.9%. Besides, LF-NPs could also prolong the release time of lily fragrance. Finally, the cytotoxicity tests indicated that LF-NPs offered biocompatibility. Therefore, LF-NPs were expected to have application prospects.
基金
financially supported by the National High Technology Research and Development Program (No. 2016YFA0200303)
the Beijing Natural Science Foundation(No. 2164071)
the National Natural Science Foundation of China (Nos. 31522023,31771095, and 51573188)
the Beijing Municipal Science & Technology Commission(No. 2161100002616015)
