227例女性患者泌尿生殖道感染支原体的培养结果及其对抗菌药物的耐药性分析

Analysis on Culture Results of Mycoplasma in Female Patients with Urogenital Tract Infection and Their Resistance to Antimicrobial Agents

目的:分析女性患者泌尿生殖道感染支原体的培养及其对抗菌药物的耐药性。方法:抽取2018年1月—2018年12月间收治的泌尿生殖道感染患者227例临床资料,分析其所采集的宫颈分泌物支原体培养结果及其对抗菌药物的耐药性。结果:227例女性泌尿生殖道感染患者中,其宫颈分泌物支原体阳性患者127例(占55.95%),其中解脲支原体感染99例占77.95%,人型支原体感染7例占5.51%,混合感染21例占16.54%;解脲支原体对交沙霉素、强力霉素、美满霉素的耐药率分别为0.00%、1.01%和2.02%;其对环丙沙星、红霉素的耐药率分别为75.76%和32.32%;人型支原体对交沙霉素、强力霉素和美满霉素的耐药率均为0.00%,而其对罗红霉素、克拉霉素和红霉素的耐药率均为100.00%。结论:临床在选用抗菌药物治疗支原体感染时,可选用交沙霉素、强力霉素和美满霉素等耐药率较低的抗菌药物,以确保患者用药的安全、有效。

Objective: To analyze the culture results of Mycoplasma in female patients with urogenital tract infection and their resistance to antimicrobial agents. Methods: Clinical data of 227 patients with urogenital tract infection who were admitted to hospital from January 2018 to December 2018 were collected to analyze the results of Mycoplasma culture of cervical secretions and their resistance to antimicrobial agents. Results: Of the 227 female patients with urogenital tract infection, 127(55.95%) were positive for Mycoplasma secreta from the cervix, among which 99(77.95%) were Mycoplasma Urealyticum infection, 7(5.51%) were Human Mycoplasma infection, and 21(16.54%)were mixed infection. The drug resistance rate of Ureaplasma Urealyticum to cisfomycin, doxycycline and metformin was 0.00%, 1.01% and 2.02%, respectively. The drug resistance rates of ciprofloxacin and erythromycin were 75.76%and 32.32% respectively. The drug resistance rate of Mycoplasma Hominis to josamycin, doxycycline and minocycline was 0.00%, and the drug resistance rate to roxithromycin, clarithromycin and erythromycin was 100.00%. Conclusion:In the clinical use of antibiotics to treat Mycoplasma infection, josamycin, doxycycline and minocycline can be selected to ensure the safety and effectiveness of the patients.