深圳市南山区47例登革热病例临床及实验室特征分析

Analysis of clinical and laboratory features of 47 patients with dengue fever in Nanshan District of Shenzhen

目的分析2014年深圳市南山区登革热患者的临床及实验室特征。方法回顾性分析2014年9—10月南山区各医院收治47例登革热住院病例的流行病学特征、临床特点以及实验室检查。结果流行病学调查显示51.1%(24/47)病例为输入性病例。临床特征为发热(100%)、皮疹(61.7%)、肌肉痛(53.2%)、骨关节痛(55.3%)为主,伴随畏寒、乏力、头痛、呕吐症状等;白细胞下降、血小板计数减少的病例分别占100%、83.0%;18例病例进行了血清分型,结果提示DENV-1感染占94.4%(17/18),DENV-2感染占5.6%(1/18)。结论 2014年深圳市南山区感染登革热患者临床表现典型, 51.1%病例为输入性病例,流行型别以DENV-1为主。

Objective To analyze the clinical and laboratory features of patients with dengue fever in Nanshan District of Shenzhen in 2014.Methods The clinical data of 47 dengue fever inpatients admitted to Nanshan from September to October in 2014 were respectively analyzed,including epidemiologic features,clinical characteristics and laboratory examinations.Results Of all the 47 patients,24(51.1%) were imported cases.The clinical characteristics included fever(100%),skin rash(61.7%),myalgia(53.2%) and bone soreness(55.3%),with intolerance of cold,feeble,headache,emesis and other simultaneous symptoms.The leucopenia and thrombocytopenia were found in 100% and 83.0% patients with dengue fever,respectively.Virus serotype detection among 18 patients showed that 94.4% patients were identified as DENV-1 infection,and 5.6% DENV-2 infection.Conclusion The clinical features of patients with dengue fever in Nanshan district of Shenzhen in 2014 were typical,with DENV-1 as the predominant serotype,including 51.1% imported cases.