血压变异性对老年高血压患者冠脉病变程度的预测价值

Predictive Value of Blood Pressure Variability on Coronary Artery Lesion in Elderly Patients with Hypertension

目的:探讨并分析血压变异性对老年高血压患者冠脉病变程度的预测价值。方法:将210例来笔者所在医院进行诊治的老年高血压患者给予冠状动脉造影,根据造影结果分为观察组(115例)和对照组(95例),并将观察组根据Gensini评分分为轻度组(49例)、中度组(37例)和重度组(29例)。分别比较各组血压变异性,并通过Pearson相关性分析血压变异性与冠脉病变程度相关指标的关系。结果:观察组患者24 h SCV、24 h DCV、dSCV、dDCV、nSCV、nDCV均明显高于对照组(P<0.05);中、重度组相关指标均显著高于轻度组,且重度组显著高于中度组(P<0.05)。Pearson相关分析显示,24 h SCV、24 h DCV、dSCV、dDCV、nSCV、nDCV均与Gensini评分呈正相关(P<0.05)。结论:在老年高血压患者中,血压变异性较大的患者更容易发生冠脉病变,降低血压变异性可能对减少血管损伤有意义。

Objective:To investigate and analyze the predictive value of blood pressure variability on coronary artery disease in elderly patients with hypertension.Method:A total of 210 elderly patients with hypertension were selected and divided into observation group(n=115) and control group(n=95) according to the results of coronary angiography.The observation group was divided into mild group(n=49),moderate group(n=37) and severe group(n=29) according to Gensini score.The blood pressure variability were compared among the groups,and the correlation between blood pressure variability and coronary artery lesion degree were analyzed by Pearson correlation analysis.The relationship between indicators.Result:24 h SCV,24 h DCV,dSCV,dDCV,nSCV,nDCV in the observation group were significantly higher than those in the control group(P<0.05),and the relative indexes in the moderate and severe group were significantly higher than those in the mild group and the moderate group(P<0.05),and in the severe group were significantly higher than those in the moderate group(P<0.05). Pearson correlation analysis showed that 24 h SCV,24 h DCV,dSCV,dDCV,nSCV and nDCV were positively correlated with Gensini score(P<0.05). Conclusion:In elderly patients with hypertension,patients with higher blood pressure variability are more likely to develop coronary artery disease,lowering blood pressure variability may be of significance in reducing vascular injury.