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伴CEP110-FGFR1阳性的8p11骨髓增殖综合征一例

8p11 myeloproliferative syndrome with CEP110-FGFR1 fusion in a child
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摘要 1例主诉为双侧腹股沟淋巴结肿大伴全身皮肤紫癜2周的患儿经骨髓细胞学检查、荧光原位杂交、融合基因检测、高通量DNA测序等方法确诊为伴CEP110-FGFR1阳性的8p11骨髓增殖综合征(EMS)。伴CEP110-FGFR1阳性的EMS患儿具有独特的临床及实验室特征,异基因造血干细胞移植能改善预后。
作者 陈梅玉 沈宏杰 晁红颖 王谦 张修文 何川 岑建农 陈苏宁 张日 朱明清 Chen Meiyu;Shen Hongjie;Chao Hongying;Wang Qian;Zhang Xiuwen;He Chuan;Cen Jiannong;Chen Suning;Zhang Ri;Zhu Mingqing(Department of Hematology, Changzhou Second Hospital Affiliated to Nanjing Medical University, Changzhou 213003, China;Department of Hematology, First Affiliated Hospital of Soochow University, Jiangsu Institute of Hematology, Key Laboratory of Thrombosis and Hemostasis of Ministry of Health, Suzhou 215006, China)
机构地区 南京医科大学附属常州市第二人民医院血液科 江苏省苏州大学附属第一医院血液科
出处 《中华儿科杂志》 CAS CSCD 北大核心 2019年第4期297-300,共4页 Chinese Journal of Pediatrics
基金 国家自然科学基金(81500103) 江苏省自然科学基金(BK20151230、BK20160283).
关键词 骨髓增殖 综合征 阳性 异基因造血干细胞移植 腹股沟淋巴结肿大 骨髓细胞学检查 荧光原位杂交 DNA测序
分类号 R551.3 [医药卫生—血液循环系统疾病]
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中华儿科杂志
2019年 第4期

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