Efficacy and influencing factors of allogeneic hematopoietic stem cell transplantation in treatment of 71 children with leukemia

To the Editor:Leukemia is a malignant proliferative disease that has become the most common malignancy in children,accounting for 40.5%of malignant cancers children.[1]Although chemotherapy can effectively treat children,some patients with high-risk and relapsed acute lymphoblastic leukemia(ALL)and acute myelocytic leukemia(AML)failed to achieve long-term relief.For these patients,allogeneic hematopoietic stem cell transplantation(allo-HSCT)is the best choice.However,many factors may impact the efficacy of allo-HSCT.We retrospectively analyzed the clinical data of 71 children with leukemia treated using allo-HSCT to observe the clinical efficacy and analyze the possible influencing factors.