呼气流速峰值在支气管哮喘诊断及评估中的应用价值

Application value of peak expiratory flow in diagnosis and evaluation of bronchial asthma

支气管哮喘(哮喘)是一种慢性异质性疾病,其主要特点为气道炎症、气道高反应性、可逆性气流受限及气道重塑,是最常见的慢性呼吸系统疾病之一。目前对于哮喘诊断缺乏特异性检查方法,仍是以治疗性诊断为主,导致存在漏诊、误诊现象。监测呼气流速峰值(PEF)变异率是国际指南推荐的可用于哮喘诊断的辅助检查方法,且PEF还可用于哮喘控制的自我监测,以利于指导哮喘的慢性管理,降低哮喘急性发作的风险。现针对PEF在哮喘的诊断和病情评估中的应用价值进行简要阐述。

Bronchial asthma (asthma) is a chronic heterogeneous disease, the characteristics are airway inflammation, airway hyperresponsiveness, reversible airflow limitation and airway remodeling, it is one of the most common chronic respiratory diseases.At present, there is no specific examination method for the diagnosis of asthma, which is still mainly based on therapeutic diagnosis, leading to the phenomenon of missed diagnosis and misdiagnosis.Monitoring the variation of the peak expiratory flow (PEF) is recommended by international guidelines that can be used for auxiliary examination methods for the diagnosis of asthma, and PEF can also be used for self monitoring on asthma control to help guide the chronic management of asthma and reduce the risk of acute exacerbation.This paper is aimed at the briefly overview about application value of PEF in the diagnosis and assessment of asthma.