胎儿心室内强光点与妊娠期糖尿病和贫血相关性研究

Intracardiac echogenic focus:correlation with pregnancy-induced complications

目的:探讨胎儿心室内强光点(ICEF)与妊娠期糖尿病和贫血相关性。方法:对3306例孕妇及胎儿的临床资料进行回顾性研究,以发现胎儿ICEF 318例的孕妇作为病例组,根据相同孕周检查的时间段选取318例无胎儿ICEF孕妇为对照组。观察比较两组孕妇75 g口服葡萄糖耐量试验、血红蛋白浓度、体重指数是否有差异性。比较两组孕妇妊娠期糖尿病或贫血的发病率是否与ICEF有相关性。结果:ICEF组与对照组在孕妇现体重指数(P<0.01)、血红蛋白浓度(P<0.05)及妊娠期贫血发病率(P<0.01)比较差异有统计学意义。在孕妇年龄、孕次、孕前体重指数、孕妇75 g口服葡萄糖耐量试验空腹血糖及妊娠期糖尿病发病率比较差异无统计学意义(P>0.05)。结论:妊娠期贫血可能是ICEF形成的影响因素。

Objective:To assess the correlation between intracardiac echogenic focus(ICEF)and pregnancy-induced complications.Methods:Retrospective fetal medical records of 3306 cases was performed,in the case group of 318 pregnant women who found fetal ICEF,and the control group was selected without fetal ICEF.The differences of 75g Oral glucose tolerance test(OGTT),hemoglobin concentration and body mass index(BMI)between the two groups were compared.The incidence of gestational diabetes mellitus or pregnancy-induced anemia and correlation with fetal ICEF was compared in two groups.Results:Fetal ICEF was significant differences in pregnancy-BMI(P<0.01),hemoglobin concentration(P<0.05)and pregnancy-induced anemia(P<0.01)in comparing with control groups.However,there was no difference in maternal age,gravida,pre-pregnancy BMI and 75 g OGTT between ICEF group and control group(P<0.01).Conclusions:Fetal ICEF is correlated with pregnancy-induced anemia.