微视野计在糖尿病视网膜病变的临床应用

Application of microperimetry in diabetic retinopathy

糖尿病视网膜病变严重影响视功能,其诊断、随访需要适当的视功能检查,糖尿病黄斑水肿治疗的安全性需要精确地评估。视网膜成像技术的进步使当前眼科诊断产生巨大革新,使医师可以发现早期视网膜改变,并记录治疗效果。然而,将视功能的主观改变与临床变化相联系仍充满挑战。微视野计使获得眼底相关量化的视网膜敏感度成为可能,正在改变着当前对糖尿病视网膜病变视功能的研究。本文对微视野计在糖尿病视网膜病变视功能评估、早期诊断、治疗评价方面的应用进行综述。

Diabetic retinopathy has an enormous impact on visual function.Adequate functional tests are mandatory to diagnose and follow diabetic retinopathy.More precisely,the visual function safety profile of any therapy for diabetic macular edema should be accurately investigated.The advances in retinal imaging technologies have led to enormous innovation towards diagnostic in current ophthalmology,enabling the practitioner to detect early retinal changes and to document treatment effects.However,it is still a challenge to correlate subjective alterations or clinical changes with visual function,still remains.Microperimetry offers the possibility to obtain an exact fundus-related quantification of retinal sensitivity,and it is changing the current approach to the functional investigation of diabetic retinopathy.In this paper,we review the literature encompassing visual function assessment,early diagnosis,and treatment evaluation of diabetic retinopathy with microperimetry.