经桡动脉介入治疗冠状动脉慢性完全闭塞病变效果观察

Therapeutic effect of transcatheter arterial intervention for chronic total occlusion of coronary artery

目的研究经桡动脉介入治疗冠状动脉慢性完全闭塞病变(CTO)的疗效。方法选取郑州大学第二附属医院2014年3月至2016年8月收治的66例CTO患者作为研究对象,均经桡动脉行经皮冠状动脉介入(PCI)治疗,分析PCI成功率、双侧造影有效率、微导管使用有效率、并发症发生情况及手术前后左心室射血分数(LVEF)。结果经桡动脉行PCI治疗,PCI成功率为72. 73%(48/66);使用微导管成功率较未使用者高,双侧造影成功率较非双侧造影高(P <0. 05);经桡动脉行PCI治疗术后3、6、12个月LVEF呈逐渐上升趋势,较术前升高(P <0. 05)。并发症发生率为6. 06%(4/66)。结论对CTO患者采取经桡动脉PCI治疗成功率高,术中采用微导管及双侧造影可明显提高成功率,还可有效改善心功能,且并发症少,值得临床推广。

Objective To study the therapeutic effect of transcatheter arterial intervention for chronic total occlusion of coronary artery(CTO).MethodsSixty-six patients with CTO treated in the Second Affiliated Hospital of Zhengzhou University from March of 2014 to August of 2016 were enrolled.All patients underwent percutaneous coronary intervention(PCI).The success rate of PCI,the efficiency of bilateral angiography,the effectiveness of microcatheter use,and complications,left ventricular ejection fraction(LVEF)before and after surgery were analyzed.ResultsThe success rate of PCI using microcatheter was higher than that of PCI without using microcatheter,and the success rate of bilateral angiography was higher than that of non-bilateral angiography(P<0.05).LVEF increased gradually at 3,6 and 12 months after PCI,higher than that before operation(P<0.05).The complication rate was 6.06%(4/66).ConclusionTransradial PCI has a high success rate in the treatment of CTO patients.Intraoperative use of microcatheter and bilateral angiography can significantly improve the success rate,but also effectively improve cardiac function,with fewer complications,and is worthy of clinical promotion.