胺碘酮联合酒石酸美托洛尔治疗急性心肌梗死并发快速心律失常的效果分析

Effect of amiodarone combined with metoprolol tartrate on acute myocardial infarction complicated with rapid arrhythmia

目的探讨胺碘酮联合酒石酸美托洛尔治疗急性心肌梗死并发快速心律失常的效果。方法选取130例急性心肌梗死并发快速心律失常患者,依照治疗方案分为对照组(65例)与观察组(65例)。对照组接受胺碘酮治疗,观察组接受胺碘酮联合酒石酸美托洛尔治疗。对比两组疗效、不良反应及治疗前后心功能指标[LVESD(左心室收缩末期内径)、LVEDD(左室舒张末期内径)、HR(心率)、LVEF(左心室射血分数)]。结果观察组总有效率92. 31%高于对照组73. 85%,差异有统计学意义(P <0. 05);治疗后观察组LVEF高于对照组(P <0. 05),HR、LVESD、LVEDD低于对照组(P <0. 05);两组均未出现明显不良反应。结论胺碘酮联合酒石酸美托洛尔治疗急性心肌梗死并发快速心律失常,可改善患者心功能,疗效显著,安全性高。

Objective To evaluate the effect of amiodarone combined with metoprolol tartrate on acute myocardial infarction complicated with rapid arrhythmia.MethodsA total of 130 patients with acute myocardial infarction complicated with tachyarrhythmia were divided into control group(65 cases)and observation group(65 cases)according to the treatment scheme.The control group received amiodarone treatment,while the observation group received amiodarone combined with metoprolol tartrate.The therapeutic effects,adverse reactions and cardiac function indexes(LVESD,LVEDD,HR,LVEF)before and after treatment were compared between the two groups.ResultsThe total effective rate of the observation group was 92.31%,higher than that of the control group 73.85%(P<0.05),the LVEF of the observation group was higher than that of the control group(P<0.05),and the HR,LVESD and LVEDD of the observation group were lower than that of the control group(P<0.05).ConclusionIn the treatment of acute myocardial infarction complicated with tachyarrhythmia,amiodarone combined with metoprolol tartrate can improve cardiac function with significant efficacy and high safety.