血清PCT、CRP与IL-6对乳腺癌手术后切口感染检测的诊断意义

Diagnostic significance of serum PCT, CRP and IL-6 for detection of incision infection after breast cancer operation

目的分析血清降钙素原(PCT)、C-反应蛋白(CRP)与白介素-6(IL-6)对乳腺癌手术后切口感染检测的诊断意义。方法选择2016年6月～2018年4月我院收治的152例乳腺癌患者为研究对象。所有患者均行手术治疗。依据术后是否发生切口感染分成对照组(未感染,n=114)和观察组(切口感染,n=38)。两组患者均于术后第2天测定其血清PCT、CRP、IL-6水平。结果观察组平均手术时间、住院时间长于对照组(P<0.05)。观察组血清PCT、CRP及IL-6均高于对照组(P<0.05)。观察组阳性率高于对照组(P<0.05)。结论血清PCT、CRP、IL-6检测用于乳腺癌手术患者,可为患者术后切口感染的预测提供良好的参照依据。

Objective To analyze the diagnostic value of serum procalcitonin(PCT),C-reactive protein(CRP)and interleukin-6(IL-6)in the detection of incision infection after breast cancer surgery.Methods A total of 152 breast cancer patients admitted to our hospital from June 2016 to April 2018 were enrolled.All patients were given surgery.According to whether the wound infection occurred after operation,the patients were divided into control group(not infected,n=114)and observation group(infected,n=38).The serum levels of PCT,CRP and IL-6 were measured in the two groups on the 2nd postoperative day.Results The average operation time and hospital stay in the observation group were longer than those in the control group(P<0.05).The serum levels of PCT,CRP and IL-6 in the observation group were higher than those in the control group(P<0.05).The positive rate of the observation group was higher than that of the control group(P<0.05).Conclusion In patients with breast cancer surgery,serum PCT,CRP and IL-6 detection can provide a good reference for the prediction of postoperative incision infection.