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GNAS1基因T393C多态性与喉癌生存率相关性 被引量:1

Correlation between GNAS1 gene T393C polymorphism and survival rate of laryngeal cancer
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摘要 GNAS1基因T393C单核苷酸多态性可促进肿瘤凋亡[1].本研究拟观察GNAS1基因T393C多态性与喉鳞状细胞癌(LSCC)生存率的相关性.一、资料与方法1.一般资料:选取2012年2月30日至2014年2月30日河南省驻马店市中心医院收治的90例LSCC患者,年龄36~75岁;男80例,女10例;TNM分期(2003版UICC):T1患者21例,T2患者45例,T3患者16例,T4患者8例.该研究通过我院伦理委员会审批.
作者 张连生 郑振宇 Zhang Litrnsheng;Zheng Zhenyu(Department of Otorhinolaryngology Head and Neck Surgery, Zhumadiun Central Hospital, Henan Province, Zhumadian 463000,China)
出处 《中华实验外科杂志》 CAS CSCD 北大核心 2019年第4期778-778,共1页 Chinese Journal of Experimental Surgery
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  • 1Fa-Jun Xie,Peng Zhao,Jun-Yan Kou,Wei Hong,Li Fu,Lin Hu,Dan Hong,Dan Su,Yun Gao,Yi-Ping Zhang.The T393C polymorphism of GNAS1 as a predictor for chemotherapy sensitivity and survival in advanced non-small-cell lung cancer patients treated with gemcitabine plus platinum[J].Cancer Chemotherapy and Pharmacology.2012(6)
  • 2Julian R. Molina,Ping Yang,Stephen D. Cassivi,Steven E. Schild,Alex A. Adjei.Non-Small Cell Lung Cancer: Epidemiology, Risk Factors, Treatment, and Survivorship[J].Mayo Clinic Proceedings.2008(5)
  • 3Friedrich Otterbach,Rainer Callies,Ulrich H. Frey,Klaus J. Schmitz,Christof Wreczycki,Rainer Kimmig,Winfried Siffert,Kurt W. Schmid.The T393C polymorphism in the gene GNAS1 of G protein is associated with survival of patients with invasive breast carcinoma[J].Breast Cancer Research and Treatment.2007(3)
  • 4Jifeng Feng,Xinchen Sun,Ning Sun,Shukui Qin,Fan Li,Hongyan Cheng,Baoan Chen,YuanDong Cao,Jun Ma,Lu Cheng,Zuhong Lu,Jiazhong Ji,Yingfeng Zhou.XPA A23G polymorphism is associated with the elevated response to platinum-based chemotherapy in advanced non-small cell lung cancer[J].Acta Biochimica et Biophysica Sinica,2009,41(5):429-435. 被引量:8
  • 5Hakan Alakus,Stefan P Mnig,Ute Warnecke-Eberz,Gül Alakus,Günther Winde,Uta Drebber,Klaus J Schmitz,Kurt W Schmid,Kathrin Riemann,Winfried Siffert,Elfriede Bollschweiler,Arnulf H Hlscher,Ralf Metzger.Association of the GNAS1 T393C polymorphism with tumor stage and survival in gastric cancer[J].World Journal of Gastroenterology,2009,15(48):6061-6067. 被引量:3

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