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MEX3A蛋白在上皮性卵巢癌组织中的表达及临床意义 被引量:3

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摘要 目的:探究MEX3A蛋白在上皮性卵巢癌组织中的表达水平及其与患者临床病理特征之间的关系。方法:免疫组化法检测46例上皮性卵巢癌、25例良性卵巢肿瘤及15例正常卵巢组织中MEX3A蛋白表达。结果:MEX3A蛋白在上皮性卵巢癌组织中的阳性表达明显高于良性卵巢肿瘤和正常卵巢组织(P<0.05),而良性卵巢肿瘤和正常卵巢组织比较则无显著差异(P>0.05)。MEX3A蛋白表达与上皮性卵巢癌的临床分期、淋巴结转移有关(P<0.05),而与患者年龄、组织分级、组织类型及有无腹水无关(P>0.05)。结论:MEX3A蛋白在上皮性卵巢癌组织中高表达,并与患者临床分期和淋巴结转移相关,在卵巢癌的发生发展中具有重要作用。
出处 《现代妇产科进展》 CSCD 北大核心 2019年第5期373-374,377,共3页 Progress in Obstetrics and Gynecology
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