哈尔滨市HIV阳性MSM抗病毒治疗服药依从性现状调查与分析

Investigation and analysis of the medication adherence among HIV-positive MSM in Harbin

目的了解哈尔滨地区人类免疫缺陷病毒(human immunodeficiency virus,HIV)感染者或获得性免疫缺陷综合征(acquired immune deficiency syndrome,AIDS)患者中HIV阳性的男男同性性行为人群(men who have sex with men,MSM)抗病毒治疗服药依从性现状以及相关影响因素,为相关部门制定特异性的干预策略提供参考.方法采用服药依从性量表、症状量表、AIDS耻辱量表进行问卷调查,运用SPSS13.0统计软件进行数据处理.结果 61名HIV阳性的MSM在过去7天内平均服药依从性为88.12%,依从性好的患者仅占52.46%;症状量表平均得分(18.48±15.38)分,AIDS耻辱量表平均得分(33.34±4.07)分;多因素Logistic回归分析结果显示,婚姻状况、AIDS耻辱得分、症状得分对服药依从性有影响(P<0.05),其中耻辱得分和症状得分是依从性危险因子(β>0,OR>1),婚姻状况是依从性保护因子(β<0,OR<1).结论哈尔滨地区HIV阳性MSM服药依从性有待于进一步提高,建议政府部门应采取综合干预措施提供MSM服药依从性.

Objective To understand the antiretroviral treatment adherence and related influencing factors among HIV-positive men who have sex with men( MSM)in Harbin and to provide reference data for the department of the local public health system to make specific intervention strategies. Methods Data were col-lected by Applied Medication Adherence Scale,Symptom Scale,and AIDS Stigma Scale. Data was analyzed by SPSS13. 0 statistical software. Results Among the 61 HIV-positive MSM,the average medication adherence was 88. 12% in the past 7 days,and only 52. 46% of patients showed good adherence. The average score of the symptom scale and AIDS stigma scale was 18. 48 ± 15. 38 and 33. 34 ± 4. 07,respectively. Multivariate logistic regression analysis showed that marriage,AIDS stigma score,and symptom score had a significant influence on medication adherence(P < 0. 05),in which AIDS stigma score and symptom score were the adherence risk fac-tors(B > 0,OR > 1),while marriage was the adherence protection factor(B < 0,OR < 1). Conclusion The medication adherence of HIV-positive MSM in Harbin needs to be further improved,and the local administration of public health needs to adopt comprehensive intervention measures to promote medication adherence of MSM.