心血管病行冠脉介入性治疗的作用

The role of coronary interventional therapy in cardiovascular disease

目的分析心血管病行冠状动脉(冠脉)介入性治疗的作用。方法 94例心血管病患者作为研究对象,随机分为A组和B组,每组47例。A组患者给予冠脉介入性治疗, B组患者给予常规内科治疗。观察比较两组患者的治疗效果、不良反应发生情况、心功能指标[左心室射血分数(LVEF)、左室收缩末期内径(LVESD)和左室短轴缩短率(LVFS)]、住院时间及住院费用。结果经治疗后, A组患者的总有效率为97.87%,明显高于B组的85.11%,差异有统计学意义(χ~2=4.919, P=0.027<0.05)。A组患者的不良反应发生率为10.64%,略低于B组的12.77%,差异无统计学意义(χ~2=0.103, P=0.748>0.05)。A组患者的LVEF(57.21±7.35)%、LVFS(28.35±5.13)%均明显高于B组的(49.31±7.22)%、(22.49±5.27)%,LVESD(47.31±6.24)mm明显小于B组的(52.33±7.94)mm,差异均有统计学意义(P<0.05)。A组患者的住院时间为(9.05±2.16)d,明显短于B组的(14.33±2.27)d,差异有统计学意义(P<0.05)。A组患者的住院费用略高于B组,但差异无统计学意义(P>0.05)。结论为心血管病患者行冠脉介入性治疗可改善其心功能,缩短住院时间,安全性较高,具有较佳的治疗效果。

Objective To analyze the role of coronary interventional therapy in cardiovascular disease. Methods A total of 94 cardiovascular disease patients as study subjects were randomly divided into group A and group B, with 47 cases in each group. Group A was treated with coronary interventional therapy, and group B was treated with conventional medical therapy. Observation and comparison were made on treatment effect, occurrence of adverse reactions, cardiac function indexes [ left ventricular ejection fraction (LVEF), left ventricular end systolic diameter (LVESD) and lventricular fraction shortening (LVFS)], hospitalization time and hospitalization costs between the two groups. Results After treatment, group A had obviously higher total effective rate as 97.87% than 85.11% in group B, and the difference was statistically significant (X^2=4.919, P=0.027<0.05). Group A had a little lower incidence of adverse reactions as 10.64% than 12.77% in group B, but the difference was statistically significant (X^2=0.103, P=0.748>0.05). Group A had obviously higher LVEF as (57.21 ± 7.35)% and LVFS as (28.35 ± 5.13)% than (49.31 ± 7.22)% and (22.49 ± 5.27)% in group B, and obviously smaller LVESD as (47.31 土 6.24) mm than (52.33 ± 7.94) mm in group B. Their difference was statistically significant (Pv0.05). Group A had obviously shorter hospitalization time as (9.05 ± 2」6) d than (14.33 ± 2.27) d in group B, and the difference was statistically significant (P<0.05). Group A had little higher hospitalization time than group B, but the difference was not statistically significant (P>0.05). Conclusion Coronary interventional therapy shows higher safety and better treatment effect for patients with cardiovascular disease, and it can improve their cardiac function and shorten the hospitalization time.