黄褐斑需要长期防治与综合管理

Melasma Needs Long-Term Prevention and Treatment, and Comprehensive Management

黄褐斑患病率较高,尤以亚洲中青年女性特别容易罹患,由于皮损主要发生于面部,常严重影响患者的容颜及身心健康。黄褐斑诊断不是很难,但治疗比较顽固且易复发,使其防治与管理常具有挑战性。最近有关黄褐斑研究的一些新发现为我们重新认识黄褐斑的发病机制提供了新依据和新观点,也为更好地管理黄褐斑提供了新策略和新思路。基于此,我们提倡"长期防治与综合管理"的治疗理念,日常以紫外线防护为主,在药物治疗中需兼顾"抑色素、控炎症、修屏障、抗老化"的原则,光电治疗还需把握好"平衡",避免可能诱发或加重黄褐斑的治疗方法或手段。

The prevalence of melasma is high, especially among young and middle-aged asian women. The lesions mainly occur on sun-exposed areas of the skin, especially the face, often resulting in mental injury. Prevention and treatment of melasma is highly challenging due to inconsistent treatment results and frequent relapses. However, recent studies revealed some new mechanisms of melisma, and provided some new strategies for better management of melasma. Based on this, we advocate the new concepte of “long-term prevention and treatment, comprehensive management” in the treatment of melasma. Photoprotection is the first principle in preventing relapse or exacerbation of melasma. The principle of “inhibiting pigmentation, controlling inflammation, repairing skin barrier function and anti-aging” should be taken into account in the medical treatment. The “balance” principle should be kept in mind in the treatment of melasma with various kinds of lasers, in order to avoid inducing or exacerbating melasma.