开放式管理联合早期家庭干预对住院精神分裂症患者情绪及疗效的影响

Effect of open management combined with early family intervention on mood and efficacy of inpatients with schizophrenia

目的了解开放式管理并早期家庭干预对住院精神分裂症患者负性情绪的发生及疗效的影响。方法选取186例精神分裂症患者作为研究对象,随机分为对照组和观察组,每组93例。其中对照组患者采取封闭式管理、无家属陪护;观察组患者以开放式管理、家属陪护以及早期家庭干预相结合的方式进行治疗。通过汉密尔顿焦虑量表(Hamilton Anxiety Scale, HAMA)、汉密顿抑郁量表(Hamilton Depression Scale, HAMD)、阳性与阴性症状量表(Positive and Negative Syndrome Scale, PANSS)评分以及1 a复发率评定负性情绪的发生率和疗效。结果治疗后,观察组患者的负性情绪发生率、PANSS得分以及1 a复发率均显著低于对照组(P<0.05或0.01)。结论开放式管理联合早期家庭干预可以显著降低住院精神分裂症患者焦虑、抑郁情绪的发生,有利于患者的康复。

Objective To investigate the effect of open management and early family intervention on the incidence of negative emotions and efficacy in inpatients with schizophrenia.Methods A total of 186 inpatients with schizophrenia were randomly divided into the Control Group and Observation Group,93 cases in each group.The Control Group received closed management with no companion of family members while the Observation Group received a combination of open management,family companion and early family intervention.The incidence of negative emotions and efficacy were assessed by the Hamilton Anxiety Scale (HAMA),the Hamilton Depression Rating Scale (HAMD),the Positive and Negative Symptoms Scale (PANSS) score,and the 1-year recurrence rate.Results Compared with the Control Group,the incidence of anxiety or depression in the Observation Group was significantly lower,and the difference was statistically significant (P<0.01).The PANSS score was significantly decreased in the Observation Group after 6 weeks of treatment (P<0.01).The 1- year recurrence rate of the Observation Group was significantly lower than that of the Control Group,and the difference was statistically significant (P<0.05).Conclusion Open management combined with early family intervention can significantly reduce the incidence of anxiety and depression in hospitalized patients with schizophrenia,thereby promoting rapid recovery of patients.